About Nozin
The Company
Global Life Technologies Corp. (GLT) is the maker of Nozin® brand products including Nozin® Nasal Sanitizer® antiseptic and Nozin® Allergy Master® products. Located in Bethesda, MD, this U.S. based company follows a mission to improve the quality of life for people by enhancing healthcare with new products based on innovative patented and patent pending technologies. These technologies are supported by substantial research, development and successful clinical trials (see information below and FAQ pages). Nozin® Nasal Sanitizer® antiseptic is used by healthcare facilities for infection control and presents a new option to safely reduce nasal carriage without antibiotics while lowering infection control costs. Our Company motto is to "enhance life through innovative health technologies".
Backed years of research and development, supported by NIH grants and successful clinical trials, Nozin products are directed at growing health maintenance and disease prevention markets. Made in the USA, Nozin products have been well received by doctors and healthcare professionals who use them and recommend them to patients. The Company intends to fulfill its mission through the development, marketing and sales of superior healthcare products throughout the world.
Scientific Steering Committee and Advisory Board
We are committed to continuing our investments in research and have enlisted the support of the scientific community by forming a Scientific Steering Committee composed of prominent scientists from major research universities in the United States. The scientists on this committee are all independently funded by the National Institutes of Health to carry out research in areas related to transmission of infectious diseases. The Steering Committee has, in turn, identified and recruited independent scientists who are recognized as the leading experts in the area of airborne diseases to carry out the studies that validate the efficacy of Nozin. Validation and support from renowned physicians and researchers is central to our aim of providing quality health products to consumers.
Dr. Richard Markham, the Chairman of GLT's Scientific Steering Committee, a Medical Doctor and renowned infectious disease specialist, is known for his groundbreaking work in the area of novel microbicides, an area that GLT is actively pursuing.
Experts such as Dr. Markham, and others, are actively contributing to the scientific direction of the Company.
The Steering Committee looks at prevention
By Dr. Richard Markham, Committee Chairman
The members of the Scientific Steering Committee are academic scientists and physicians who are committed to the field of Public Health. This means that much of their research has focused on the issue of disease prevention, as opposed to disease treatment. Disease prevention is an area that, in the past, has received less attention from the medical community. Most physicians, after all, are trained to treat patients who come to them with an illness. But as the costs of medical treatment continue to climb it has become clear that simpler approaches, which make disease prevention accessible to all individuals, must be developed.
One approach that has proved useful is the development of antiseptics such as alcohol-based hand sanitizers to help reduce the risk of infection by decreasing potential exposure to pathogens. But for many infections the hands serve only as the vehicle that carries germs to the site where infection is actually initiated and introduced into the body, such as the eyes, mouth and especially the nose. It is this concept of attacking infections at the site where the acquisition process actually begins that attracted the scientists who are members or advisors of the GLT Scientific Steering Committee. It is the scientists' goal to use rigorous scientific analysis to ensure that products such as Nozin® Nasal Sanitizer® antiseptic are the most effective they can possibly be.
Research
The American Journal of Infection Control (AJIC) has published the article: “Reduction of nasal Staphylococcus aureus carriage in health care professionals by treatment with a nonantibiotic, alcohol-based nasal antiseptic”
This important study demonstrated that Nozin Nasal Sanitizer® antiseptic decreased Staph aureus and total bacterial carriage, ” suggesting the usefulness of this approach as a safe, effective and convenient alternative to antibiotic treatment.” The clinical study was conducted at the Medical University of South Carolina (MUSC). The Nozin study record detail is listed at clinicaltrials. gov, a web based resource on clinical studies maintained by the National Library of Medicine (NLM) at the National Institutes of Health (NIH).
Please read below and also click on the Evidence menu above for more information. Be sure to visit nozinpro.com , the Nozin site for healthcare professionals.
Contributing Labs
Extensive studies were undertaken to demonstrate that Nozin® Nasal Sanitizer® antiseptic is a safe, highly effective anti-microbial that provides long lasting action to help reduce the risk of infection. These studies were conducted at leading independent US testing centers specializing in antimicrobial and personal care product testing. All studies are statistically designed using Good Laboratory Practices (GLPs) to ensure FDA/EPA regulatory compliance. The following are some of the results from these tests.
Nozin Nasal Sanitizer antiseptic kills germs in lab tests
Summary: In laboratory tests conducted at several leading testing facilities, and under GLP testing protocols, Nozin® Nasal Sanitizer® antiseptic was effective in killing at least 99.99% of bacterial pathogens such as staph aureus, strep pneumoniae, strep pyogenes, mycobacterium smegmatis.
Summary: While it is difficult to simulate the varied conditions of the human nose in an in-vitro model, there are surrogate tests that have been developed to help simulate these conditions. One such surrogate study is the use of a biofilm to help model in-vivo conditions.
This study examined the ability of Nozin® Nasal Sanitizer® antiseptic to inhibit the growth of bacteria in biofilms over a period of up to 12 hours. Staphylococcus aureus, the challenge strain selected for the experiment and a pathogen commonly found to colonize the nares of healthcare personnel, was challenged with four test materials.
Results: Compared to control treatments, Nozin® Nasal Sanitizer® antiseptic substantially reduced the bacterial growth even in the protective environment of the biofilm.
Nozin Nasal Sanitizer controls germs for hours in human subjects
Summary: The effect of Nozin® Nasal Sanitizer® antiseptic on the growth of bacteria in the nose was tested by applying Nasal Sanitizer® antiseptic or a control reagent to the noses of 30 subjects. The number of bacteria recovered from the nose was then determined over a 12 hour period following the application. The number of bacteria recovered from the group treated with Nozin® Nasal Sanitizer® antiseptic was reduced by 90% compared to the control-treated group.
Results: Nozin inhibits the growth of bacteria in the nose and this effect lasts for up to 12 hours.
Nozin Nasal Sanitizer is shown to be safe in dermal toxicity and skin irritation study
Summary: Nozin® Nasal Sanitizer® antiseptic was tested in human subjects to determine whether it could induce direct toxic effects to the skin or whether it could stimulate the development of allergic responses. To test the toxic effect, Nozin® Nasal Sanitizer® antiseptic was applied to a single location on the skin of the subjects once daily for 21 days. It's ability to produce toxic effects was compared to a 0.1% solution of Sodium Lauryl Sulfate, a common ingredient in soaps, shampoos, and other skin and hair care products. After a rest period of 2 weeks, Nozin® Nasal Sanitizer® antiseptic was reapplied to see if an allergic response had developed.
Results: Compared to the commonly used Sodium Lauryl Sulfate, there was no evidence of toxicity or allergic responses induced by Nozin® Nasal Sanitizer® antiseptic. Subjects did not become sensitized to Nozin® Nasal Sanitizer® antiseptic and none of the subjects experienced an increase in skin irritation up to seventy-two (72) hours following the challenge exposure of three (3) weeks.
Nozin Nasal Sanitizer®: Defense that makes sense®
Nozin® Nasal Sanitizer® antiseptic is an innovative, patented product that benefits consumers, health professionals and their patients by providing extra protection against germs. In the past decade, hand sanitizers have become recognized and popularly used to deter transmission of germs. Because hand-to-nose contact is an important mechanism for the transmission of infection, it can be beneficial to sanitize the skin on the nose as well as on the hands.
Nozin Nasal Sanitizer® antiseptic is specially formulated for the vulnerable and sensitive skin at the distal area of the nose (nasal vestibule) and helps control germ populations that come to reside there. Lab tests show that Nozin Nasal Sanitizer® antiseptic kills harmful germs. Human trial results show that one application of Nozin Nasal Sanitizer® antiseptic can be effective for over eight hours (see above test summaries and results).
Unlike many existing products that purport to offer protection, Nozin® Nasal Sanitizer® antiseptic is unique in that it attacks germs at the nose which is a known reservoir for microbial colonization. The Center for Disease Control already heavily promotes the importance of frequent hand washing and of hand sanitizers in helping prevent germs residing on hands from being 
transmitted to the nose. Nozin® Nasal Sanitizer® antiseptic directly targets the skin at the front of the nose, the nasal vestibule, a critical site of germ transmission. Nozin Nasal Sanitizer antiseptic adds a targeted, long-acting level of defense by helping to shield your nose. Regular use of Nozin Nasal Sanitizer antiseptic in conjunction with hand washing could provide a very effective hygienic regimen which can help reduce the risk of infection.
Many top physicians and scientists realize the compelling logic of hygienic innovation that Nozin offers. Nozin Nasal Sanitizer antiseptic is a professionally valued and sensible approach in the effort to reduce the risk of infection.
Significance of Nozin
Studies indicate that the active ingredient in Nozin® Nasal Sanitizer® antiseptic is safe and has substantial activity against a wide variety of pathogenic organisms. The research also shows that the Nasal Sanitizer® Nozaseptin™ formulation has activity that persists for hours after application.
We believe that the observation that Nozin Nasal Sanitizer antiseptic persists for hours after application at the site of potential infection has important implications to help reduce risk of germs. In light of the ubiquitous occurrence and medically important consequences of infections, and the evidence that a topical antiseptic can be beneficial, this simple and safe intervention could be an effective aid in the reduction of infections.
Conclusion: Benefits of using Nozin Nasal Sanitizer®
Many of us are aware that every time we are in a crowded plane, bus, train, or in other settings such as hospitals, we may be more likely to be exposed pathogens.
Better health and enhanced lifestyle can be key benefits of adopting a sound hygienic routine. Consumers who adopt and commit to a low-cost and effective hygienic regimen know they are doing something to help ensure their health and improve their quality of life.
Top physicians and scientists realize that the hygienic benefits Nozin® Nasal Sanitizer® antiseptic offers could provide critical first line defense in high risk, crowded or confined areas (e.g. airplanes, offices, athletic facilities, schools, theaters, hospitals, nursing homes, etc). Nozin® Nasal Sanitizer® antiseptic can help reduce the risk of infection as an important part of health maintenance and in the fight against germ transmission.
