Antimicrobial Stewardship Boosts Outcomes for MRSA

April 14, 2016

Daily monitoring of patients receiving antimicrobial injections targeting methicillin-resistant Staphylococcus aureus (MRSA) is associated with improved clinical outcomes, according to a study published online in the Journal of Clinical Pharmacy and Therapeutics. The study included daily reviews of prescriptions and the review occurred within 24 hours after initiation of therapy. 

The researchers found that implementation of daily review correlated with a significant reduction in the time to administer effective antimicrobials (median number of days, three versus zero; P < 0.001) and with a significant elevation in the rate of de-escalation (47.1 versus 96.2%; P < 0.001). After the intervention, there was a significant reduction in 60-day clinical failure associated with gram-positive bacterial infection (33.3 versus 17.6%; P = 0.007).

"Daily review of administration of antimicrobials targeting MRSA was highly effective in improving clinical outcomes by optimizing early antimicrobial therapy," was reported by the authors.

See the Full Study at the Journal of Clinical Pharmacy and Therapeutics

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